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{
    "metadata": {
        "accession": "Q9VT00",
        "id": "JARD2_DROME",
        "source_organism": {
            "taxId": "7227",
            "scientificName": "Drosophila melanogaster",
            "fullName": "Drosophila melanogaster (Fruit fly)"
        },
        "name": "Jumonji, AT rich interactive domain protein 2",
        "description": [
            "Regulator of histone methyltransferase complexes (By similarity). Involved in the establishment or maintenance of higher order chromosome compaction and closed euchromatin structure (PubMed:17970746). Accessory component of the polycomb repressive complex 2 (PRC2) involved in maintenance of transcriptional repression and regulation of transcriptional activation or elongation; functions in a PRC2-dependent and PRC2-independent manner (PubMed:22354997). Reduces levels of H3K27me3 histone modification (PubMed:22354997)"
        ],
        "length": 2351,
        "sequence": "MVVSKDNNKRRRKETETPPPPPPVPPAGSSLAPPSAVAAIESSPEMPKRTKVQAQRKFAQGQSAPSSSSSIAYSAAAAAAGSGSGPSTSGADSNQPPIEILPNKCPKPQDFLTFLCFRGTRALPAHLDFLNQGKSKDSEASSTGANNNNNARKPNNSRASLAGNKKKRGRPAKGATKKVDVVAPIPDPTEKPSTAEKPASDKNNLIAAEAPKIPSRNPTPVLPGAVRKRAEVVTDGNRRGARGRGAGISHDKTTPAALSKDNKRRSNRASTKESKPVIDDDNSEDLDEQEADDDEDEFFSAHDATSRNGEEVKADSPVKAEPTKRGRPSAAKKAVEPAPEGQTVLKDKAPVKRVRQRESPIFIPSPESSGRMTRQRAFFEPVKVPPHKEEPGAHDPPKDEPKKQPETPPSKTEKEQEPTKQIKEAKEKTNSSIYAKEAKQQLENGDSLHGAVAKGKKSLNVFDFSSDDEQPLAKSIKLKKGAKGASPKKGGAAPIAPAARNRKAAAKKLDKEKEIEKEKQREKEEEIERDKAKEKKDKEKEKEKEKHPVPESKVEEPPSGGKRGKAGKKKAEDAPADEEDLAPPSSKKVATNARGSRKSAKSKASEDSAELEPQRSQRPSRKTKEAAAIYMGIIGHKLQLADDEEDDLSMSSFPDIPNVKEMEKMENEIKRNAAGKLNVPEASTVLSAGKSTRKPSPRPKDSPVTAPVEATRNESPSPPEAEEEKPPPPARRGRPPKQNKVNAGPAHKPRIEGMLVKKGSLAKMSEQQAKPKAKSEHSKVDSDEEEDFLINEELNETKRKLEKSFSDSDDEPLAIKVPAVAVKEKELLPPKMASPPPKLVPVPSPISVPTPAVSVAPSLAVPSILPTSTGTTQLTMLPLTAKATSSLGSMPMFPSIQASYSPLKTMEKKPPVPTSKILNVPATYALPGSASGAVSFQKTSSYLPQASPHYHSGYVRPPPTPTHQFGGGAPSGSKTPSQGSSPLKYQTPPTTYPPPIEAYQCPKINPNFLTPKYERSPLPRSSTSSFPSPSPVKFQPTSGTTATTVGTPSSATKSPLAPPPPSPPVSQVVIQTSSLNLSMSIAATVNAAPMPVASTSAAAAHQTTVATTVTATSTPPPAHSNSAATGGGAGANSDPLKDEIGSILAQATLMPSKEESGKIFGIASVSLAQSSGPDNTKCTLGKCGSIHKPVLGPVVPTEGYFGDQLSSKERRKAKVNMTHEQIQKWLIECSSNPDEIQDDLDDDFDDSLRPQQSTTPPPTRDDKELSASFSSSSKNTRGDLGKSESAWSAKGPSLKATPVLVTPPNRKELHEQADSKDCDALDYDKSSTPVNLTQKITSNESLAVEKKVNDRKGKESAKAAASKAATQPRSTAATPPTPISSTPTPASLTPSKSSPTPPPAVKQKAEKGKRNATAGGGATALASPPAAPTPANPKRTPVYNQKNAKAQQQQAETKPASNPPSGAGTKRESVYAFGKDDESGSKSGNRRRTDPSPVPAPALVPNALSERSPTKKRAAAAAAATAVQLTLSPTENCKIEGKPSKAPTGRGAKKQQQQAPAPPAPPVEASGDSDAEGATFYIPLQGAGVGGSGDGGIQGVAVKLGREGPDGPNQKVVMQATLVTKAQMDTNSKPLPESLNTNELVKTLLHAASNDAASTTTSLKSLPKASTSAAAGAAAAPGASSLVRVNSNSSLFSGSAKSRTAAQTSSTAAAVAKKYKDDTPIKMANNTAFPRHDDPTQMVEAPIFRPTEKEFADPIEFIERITPIAARFGICKIIPPASFKPECRISDEMRFTAYNQYVHKMLHRWGPSAKELSAIKKYLATQSIVMNHPPWIGGMEVDLPRLYHTVQELGGLKEVIEKKKWARVAEEMCIPKLAQDRVTKLDDIYCKYLLPYDTLSPAERQKLFDEVEADWAKREARARRNADRFVNTESVSNEEDDLSSDEDEESEEEIDGVSMECIVKGRSMPLSQFYRIARNTMALWFKSTDPTVNEVEAEFWRHVAVRDSHVCVHSGSIDSSGWGYGFPSPGPKGKGSNYARHPWNLKVLTNNSGSVLRSLGPVMGVTVPTLHVGMLFSACCWYRDPHGLSWIEYLHTGASKLWYGIPDDQSANFRAALTSLIPTHCQNKTIWLPCDTVMVPPHMLTDRGVSLCRIEQKPGEFIVVFPRAYTSSLATGYVVSESVYFATMSWLDLAKDDFRDIHESCEPAMFSLEQLLFALGYDQRVNSEALHQMLPMLNDVCEKESAAREQLRAAGVTSTEKVQAEKGQKAKKQQQPPYKSIESECDLCRANLYISMVRTEDGNIYCLQHALKNLNNGNIQAKQCKLIYAYNVDDIQQLIRQLQEKINHKAAVKKK",
        "proteome": "UP000000803",
        "gene": "Jarid2",
        "go_terms": [
            {
                "identifier": "GO:0003677",
                "name": "DNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 1,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "6995496f5e9633491d147c7f4621a28b9f76d856",
        "counters": {
            "domain_architectures": 1531,
            "entries": 22,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "smart": 4,
                "cathgene3d": 2,
                "profile": 3,
                "ssf": 2,
                "cdd": 1,
                "pfam": 4,
                "panther": 1,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1531
        }
    }
}