{"metadata":{"accession":"Q9U1W1","id":"TFG_CAEEL","source_organism":{"taxId":"6239","scientificName":"Caenorhabditis elegans","fullName":"Caenorhabditis elegans"},"name":"Protein tfg-1","description":["In its hexameric form, promotes the accumulation of sec-16A.1 and the COPII subunit npp-20 at endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER), to positively regulate secretory cargo trafficking from the endoplasmic reticulum to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) and Golgi apparatus (PubMed:21478858). Required for the assembly of proteins, such as the GTPase rab-6, at the Golgi apparatus (PubMed:21478858). Plays a role in negatively regulating cell death and promoting cell and body growth (PubMed:18635357)"],"length":486,"sequence":"MVHSNGAITSTILKARHADVVRKTSLHHANDLTLIDLVLNVQRLLALPSDANFVLKYKDEEGDLVTLAEDSDLLLALHTSGATLDVTVVVDSRAREAVHDVQKQVEQIKLDVGKLLGALSALDVAQIAEQSNTSVANLSAPKQSHHDNIVFQKSFEAAPPSPVPSEKAELPATIQPSVHEQFNHRPAHVEEEIPLENHYAPPPHQQIPDDLNTSFSSQPPPPIEQFGAIPPPNATIPSFPTSNAASPPVQEFAPPPPQQQQQQFQAPPPPMASHSSISSTPVQQQGFAPPQQFGGPPPSGPPSEYGGYAPPQQQQQQFGAPPPQGAPQQGFGAPPQGPPQGGPPQGSFGAPPPQQFHAPSPQSFGGPPPPVSSAPGNFAPPPQSGPPGAFAPPPSAFGAPQGPGGPGGYGPPPPGGPGAPGSYGPPQGGPGGFGPPPPGGPGAYGPPPTGFPPVGAPPPGAAGAPGGNPFARGPSATGYRQSPYQQ","proteome":"UP000001940","gene":"tfg-1","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0042802","name":"identical protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006888","name":"endoplasmic reticulum to Golgi vesicle-mediated transport","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0048208","name":"COPII vesicle coating","category":{"code":"P","name":"biological_process"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"8d3857a1059b3cbb988e2e6ea38867b08db5bfdd","counters":{"domain_architectures":12883,"entries":9,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"profile":1,"smart":1,"pfam":1,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":12883}}}