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{
    "metadata": {
        "accession": "Q9LVM5",
        "id": "TTHL_ARATH",
        "source_organism": {
            "taxId": "3702",
            "scientificName": "Arabidopsis thaliana",
            "fullName": "Arabidopsis thaliana (Mouse-ear cress)"
        },
        "name": "Uric acid degradation bifunctional protein TTL",
        "description": [
            "Involved in the last two steps of the degradation of uric acid, i.e. the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) and its stereoselective decarboxylation to (S)-allantoin, a major ureide compound (PubMed:20167108, PubMed:20511299). Might function as a negative regulator to modulate brassinosteroid-mediated plant growth (PubMed:15319482). Together with B1L, prevents plant growth and development, but by opposition to B1L, negatively regulates cold tolerance, probably in a brassinosteroid (BR) and allantoin-dependent manner (PubMed:32664862)"
        ],
        "length": 324,
        "sequence": "MAMEIGEDEWKVCCGSSEFAKQMSTSGPLTSQEAIYTARDIWFNQVNVTDWLEAFSAHPQIGNTPSPSINSDFARRSVSEQSTAFATTSASALQELAEWNVLYKKKFGFIFIICASGRTHAEMLHALKERYENRPIVELEIAAMEQMKITELRMAKLFSDKAKVISETDSSSSPVSTKPQDRLRIIGGHLNVAAEAKAPKRSRPPITTHVLDVSRGAPAAGVEVHLEVWSGTTGPSFVHGGGGVWSSVGTSATDRDGRSGPLMDLVDALNPGTYRISFDTAKYSPGCFFPYVSIVFQVTESQKWEHFHVPLLLAPFSFSTYRGS",
        "proteome": "UP000006548",
        "gene": "TTL",
        "go_terms": [
            {
                "identifier": "GO:0033971",
                "name": "hydroxyisourate hydrolase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006144",
                "name": "purine nucleobase metabolic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 1,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "ida_accession": "1840bcadfdabb9e5a19abb97ba5af601e8f43595",
        "counters": {
            "domain_architectures": 899,
            "entries": 22,
            "isoforms": 3,
            "proteomes": 1,
            "sets": 2,
            "structures": 1,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "ssf": 2,
                "pfam": 2,
                "cdd": 1,
                "pirsf": 1,
                "panther": 1,
                "ncbifam": 1,
                "prosite": 2,
                "prints": 1,
                "interpro": 9
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 899
        }
    }
}