{"metadata":{"accession":"Q9LD14","id":"PILR1_THUPL","source_organism":{"taxId":"3316","scientificName":"Thuja plicata","fullName":"Thuja plicata (Western red-cedar)"},"name":"Bifunctional pinoresinol-lariciresinol reductase 1","description":["Reductase involved in lignan biosynthesis. Catalyzes the enantioselective sequential conversion of (-)-pinoresinol into (-)-lariciresinol and of (-)-lariciresinol into (+)-secoisolariciresinol. Can also convert with a lower efficiency (+)-pinoresinol into (+)-lariciresinol, but not (+)-lariciresinol into (-)-secoisolariciresinol. Abstracts the 4R-hydride from the NADPH cofactor during catalysis"],"length":313,"sequence":"MDKKSRVLIVGGTGYIGKRIVNASISLGHPTYVLFRPEVVSNIDKVQMLLYFKQLGAKLIEASLDDHQRLVDALKQVDVVISALAGGVLSHHILEQLKLVEAIKEAGNIKRFLPSEFGMDPDIMEHALQPGSITFIDKRKVRRAIEAASIPYTYVSSNMFAGYFAGSLAQLDGHMMPPRDKVLIYGDGNVKGIWVDEDDVGTYTIKSIDDPQTLNKTMYIRPPMNILSQKEVIQIWERLSEQNLDKIYISSQDFLADMKDKSYEEKIVRCHLYQIFFRGDLYNFEIGPNAIEATKLYPEVKYVTMDSYLERYV","proteome":null,"gene":"PLR_Tp1","go_terms":[{"identifier":"GO:0016491","name":"oxidoreductase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"0a73fd4be2365872a9361705544819c1de24850c","counters":{"domain_architectures":69641,"entries":10,"isoforms":0,"proteomes":0,"sets":2,"structures":1,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":2,"cdd":1,"pfam":1,"panther":1,"interpro":4},"proteome":0,"taxonomy":1,"similar_proteins":69641}}}