{"metadata":{"accession":"Q9KQJ8","id":"Q9KQJ8_VIBCH","source_organism":{"taxId":"243277","scientificName":"Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)","fullName":"Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)"},"name":"Glyceraldehyde-3-phosphate dehydrogenase","description":["Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG"],"length":331,"sequence":"MTIKVGINGFGRIGRFVFRAAQERNDIEIVGINDLIDVDYMAYMLKYDSTHGRFNGTVEVKDGNLIVNGKTVRVTAERNPADLKWGEIGVDVVAEATGLFLTDETARKHIEAGAKKVVLTGPSKDKTPMFVMGVNHKTYAGQDIVSNASCTTNCLAPIAKVLNDNFGIESGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGVVLPELNGKLTGMAFRVPTANVSVVDLTVNLQKAASYDDIKAAMKAASEGELAGILGYTEDAVVSTDFNGDTRTSIFDADAGIALTDKFVKVVSWYDNEIGYSNKVLDLIAHISK","proteome":"UP000000584","gene":"VC_2000","go_terms":[{"identifier":"GO:0051287","name":"NAD binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016620","name":"oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0050661","name":"NADP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006006","name":"glucose metabolic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"86e234e29d479086cc42dd5d3ba81d154e67c69b","counters":{"domain_architectures":60723,"entries":20,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"pfam":2,"cdd":2,"smart":1,"ssf":2,"cathgene3d":2,"pirsf":1,"panther":1,"ncbifam":1,"prints":1,"prosite":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":60723}}}