{"metadata":{"accession":"Q9I970","id":"Q9I970_ONCMY","source_organism":{"taxId":"8022","scientificName":"Oncorhynchus mykiss","fullName":"Oncorhynchus mykiss (Rainbow trout)"},"name":"Lymphotoxin-alpha","description":["Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo"],"length":246,"sequence":"MEGYAMTPEDMERGPVYNTTVTAVAEGKASRGWLWRLCGVLLIAGLCAAAALLFAWCQHGRPSTMQDEIEPQLEILIGAKDTHHTLKQIAGNAKAAIHLEGEYNPNLSADTVQWRKDDGQAFSQGGFELQGNQILIPHTGLFFVYSQASFRVKCNSPGEHTTPLSHIIWRYSDSIGVNANLLSGVRSVCQQNYGDAESKIGEGWYNAVYLGAVFQLNEGDKLWTETNRLTDVEPEQGKNFFGVFAL","proteome":null,"gene":"tnfa","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005164","name":"tumor necrosis factor receptor binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006955","name":"immune response","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"452ab3949debfc11bfeb581670598a02215fe991","counters":{"domain_architectures":12863,"entries":11,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cdd":1,"cathgene3d":1,"smart":1,"profile":1,"pfam":1,"panther":1,"prints":1,"interpro":3},"proteome":0,"taxonomy":1,"similar_proteins":12863}}}