{"metadata":{"accession":"Q9CXV0","id":"ISL2_MOUSE","source_organism":{"taxId":"10090","scientificName":"Mus musculus","fullName":"Mus musculus (Mouse)"},"name":"Insulin gene enhancer protein ISL-2","description":["Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways"],"length":359,"sequence":"MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAQCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPSLRTHVHKQAEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKASLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET","proteome":"UP000000589","gene":"Isl2","go_terms":[{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000981","name":"DNA-binding transcription factor activity, RNA polymerase II-specific","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0045944","name":"positive regulation of transcription by RNA polymerase II","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0048665","name":"neuron fate specification","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0006355","name":"regulation of DNA-templated transcription","category":{"code":"P","name":"biological_process"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"9df4db78da89de75c996e6971cfd5463e5e014f5","counters":{"domain_architectures":13971,"entries":22,"isoforms":0,"proteomes":1,"sets":4,"structures":2,"taxa":1,"dbEntries":{"ssf":2,"profile":2,"smart":2,"cdd":3,"cathgene3d":2,"pfam":2,"panther":1,"prosite":2,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":13971}}}