{"metadata":{"accession":"Q9BS18","id":"APC13_HUMAN","source_organism":{"taxId":"9606","scientificName":"Homo sapiens","fullName":"Homo sapiens (Human)"},"name":"Anaphase-promoting complex subunit 13","description":["Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (PubMed:15060174, PubMed:18485873). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (PubMed:15060174, PubMed:18485873). The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins (PubMed:29033132)"],"length":74,"sequence":"MDSEVQRDGRILDLIDDAWREDKLPYEDVAIPLNELPEPEQDNGGTTESVKEQEMKWTDLALQYLHENVPPIGN","proteome":"UP000005640","gene":"ANAPC13","go_terms":[{"identifier":"GO:0005680","name":"anaphase-promoting complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"10264413fe49b2a99827108cd93d0baa95df056c","counters":{"domain_architectures":2302,"entries":3,"isoforms":0,"proteomes":1,"sets":0,"structures":20,"taxa":1,"dbEntries":{"pfam":1,"panther":1,"interpro":1},"proteome":1,"taxonomy":1,"similar_proteins":2302}}}