{"metadata":{"accession":"Q96J88","id":"ESIP1_HUMAN","source_organism":{"taxId":"9606","scientificName":"Homo sapiens","fullName":"Homo sapiens (Human)"},"name":"Epithelial-stromal interaction protein 1","description":["Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation (By similarity). Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages (By similarity)"],"length":318,"sequence":"MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQSGGCWNMNSGNSWGI","proteome":"UP000005640","gene":"EPSTI1","go_terms":null,"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"9e1ba7197a2d19fe9237edfc9b3a610e24b6445d","counters":{"domain_architectures":1064,"entries":3,"isoforms":3,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"panther":1,"pfam":1,"interpro":1},"proteome":1,"taxonomy":1,"similar_proteins":1064}}}