{"metadata":{"accession":"Q8ZVI1","id":"ENDA_PYRAE","source_organism":{"taxId":"178306","scientificName":"Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)","fullName":"Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)"},"name":"tRNA-splicing endonuclease","description":["Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp"],"length":183,"sequence":"MIGYLRGLAVIVEDVEFARRLYKEGFYGRFLGYDKVKRDEVEKINAPLILGLYEALYLAEKGRLKVMGEDGREVAPEELAALGRERMRNFDEIYKIYKYFRDLGYVVKSGLKFGALFSVYEKGPGIDHAPMVVVFLEPDKGISATDITRGGRLSHSVRKTWTLATVLRQTGEVVLLGFGWARL","proteome":"UP000002439","gene":"endA","go_terms":[{"identifier":"GO:0000213","name":"tRNA-intron lyase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006388","name":"tRNA splicing, via endonucleolytic cleavage and ligation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0003676","name":"nucleic acid binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"941abee8bd23336a20187cbb8cd57119e9ef0738","counters":{"domain_architectures":2064,"entries":18,"isoforms":0,"proteomes":1,"sets":3,"structures":1,"taxa":1,"dbEntries":{"pfam":2,"ssf":2,"cathgene3d":2,"cdd":1,"hamap":1,"pirsf":1,"panther":1,"ncbifam":1,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":2064}}}