{"metadata":{"accession":"Q8UY66","id":"Q8UY66_9ADEN","source_organism":{"taxId":"175567","scientificName":"Simian adenovirus 25","fullName":"Simian adenovirus 25"},"name":"33 kDa","description":["Plays a major role to prevent cellular inhibition of viral genome replication by nuclear bodies. Assembles an SCF-like E3 ubiquitin ligase complex based on the cellular proteins ELOB, ELOC, CUL5 and RBX1, in cooperation with viral E1B-55K. This viral RING-type ligase ubiquitinates cellular substrates prior to proteasomal degradation: p53/TP53, LIG4, MRE11-RAD50-NBS1 (MRN) complex, ITGA3, DAXX and BLM"],"length":301,"sequence":"MSESNCIMTRSRTRSAASRHHPYRPAPLPRCEETETRASLVEDHPVLPDCDTLSMHNVSSVRGLPCSAGFAVLQEFPVPWDMVLTPEELRVLKRCMSICLCCANIDLFSSQMIHGYERWVLHCHCRDPGSLRCMAGGAVLALWFRRIIRGCMFNQRVMWYREVVNRHMPKEIMYVGSVFWRGHHLIYLRIWYDGHVGSILPAMSFGWSVLNYGLLNNLVVLCCTYCSDLSEIRMRCCARRTRRLMLRAVGIMLRESLDPDPLSSSLTERRRQRLLRGLMRHHRPIPFADYDSHRRSSASSR","proteome":null,"gene":"E4","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":false,"in_bfvd":false,"ida_accession":"74b2836dadd9d75a8335e8fe225f132fd14098ab","counters":{"domain_architectures":329,"entries":2,"isoforms":0,"proteomes":0,"sets":0,"structures":0,"taxa":1,"dbEntries":{"pfam":1,"interpro":1},"proteome":0,"taxonomy":1,"similar_proteins":329}}}