{"metadata":{"accession":"Q8IE14","id":"SEC11_PLAF7","source_organism":{"taxId":"36329","scientificName":"Plasmodium falciparum (isolate 3D7)","fullName":"Plasmodium falciparum (isolate 3D7)"},"name":"Signal peptidase complex catalytic subunit SEC11","description":["Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:18054093, PubMed:30127496). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity)"],"length":184,"sequence":"MDFIKEQYNSLVLDLRKTFRNKRDGLSHILNVICLLLNALMIWKLLVVFTGCESPVVVVLSGSMEPGYYRGDTLALYHPPKIHAGDVVVYQINGRDIPIVHRILSLHTSKDNKFHLLSKGDNNNIDDRGLYDPHQYWLENEHVLGLSVGYTPYIGILTIWINEYPVVKWAIVSIMLIMILMGYE","proteome":"UP000001450","gene":"SEC11","go_terms":[{"identifier":"GO:0004252","name":"serine-type endopeptidase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006465","name":"signal peptide processing","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0008233","name":"peptidase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"21a303415f586161a7ae3f861798b3e824195375","counters":{"domain_architectures":27568,"entries":12,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"pfam":1,"cdd":1,"panther":1,"ncbifam":1,"prints":1,"prosite":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":27568}}}