{"metadata":{"accession":"Q8GYB8","id":"OPR2_ARATH","source_organism":{"taxId":"3702","scientificName":"Arabidopsis thaliana","fullName":"Arabidopsis thaliana (Mouse-ear cress)"},"name":"12-oxophytodienoate reductase 2","description":["Specifically cleaves olefinic bonds in alpha,beta-unsaturated carbonyls and may be involved in detoxification or modification of these reactive compounds (Probable). May be involved in the biosynthesis or metabolism of oxylipin signaling molecules (Probable) (PubMed:10872231). In vitro, reduces 9R,13R-12-oxophytodienoic acid (9R,13R-OPDA) to 9R,13R-OPC-8:0, but only poorly 9S,13S-OPDA, the natural precursor of jasmonic acid (JA) (PubMed:10872231). Can detoxify the explosive 2,4,6-trinitrotoluene (TNT) in vitro and in vivo by catalyzing its nitroreduction to form hydroxylamino-dinitrotoluene (HADNT) (PubMed:19605548). Functions in an alternative and OPR3-independent pathway for JA biosynthesis (PubMed:29291349). Catalyzes the NADPH-dependent reduction of 4,5-didehydrojasmonates to jasmonates (PubMed:29291349)"],"length":374,"sequence":"MEMVNAEAKQSVPLLTPYKMGRFNLSHRVVLAPLTRQKSYGSVPQPHAILYYSQRTSPGGFLIAEATGVSDTAQGYPDTPGIWTKEHVEAWKPIVDAVHAKGGIFFCQIWHVGRVSNRGFQPRRQAPISCTGKPIMPQMRANGIDEARFTPPRRLSIEEIPGIVNDFRLAARNAMEAGFDGVEIHGAHGYLIDQFMKDKVNDRTDEYGGSLQNRCKFALEVVDAVAKEIGPDRVGIRLSPFADYMESGDTNPEALGLYMVESLNKYGILYCHMIEPRMKTVGEIAACSHTLMPMREAFKGTFISAGGFTREDGNEAVAKGRTDLVAYGRWFLANPDLPKRFQLDAPLNKYNRSTFYTSDPVVGYTDYPSLESTA","proteome":"UP000006548","gene":"OPR2","go_terms":[{"identifier":"GO:0010181","name":"FMN binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016491","name":"oxidoreductase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"e395385a5c05a3b7668e74bd6bb58ef6b9be4b15","counters":{"domain_architectures":72067,"entries":8,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"cdd":1,"ssf":1,"pfam":1,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":72067}}}