{"metadata":{"accession":"Q71KT5","id":"ERG24_MOUSE","source_organism":{"taxId":"10090","scientificName":"Mus musculus","fullName":"Mus musculus (Mouse)"},"name":"Delta(14)-sterol reductase TM7SF2","description":["Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis"],"length":418,"sequence":"MTSREASQAPLEFGGPLGVAALLILLPATMFHLLLAARSGPARLLALPAYLPGLEELWSPWALLLLFIWLGLQVALYLLPARKVAEGLELKDKSRLRYPINGFQALVLTALLMGLGVSVGLPLGALPGMLLPLAFATTLTSFIFSLLLYAKALVAPASALAPGGNSGNSMYDFFLGRELNPRLGSFDFKYFCELRPGLIGWVFINLALLMQEAELRGSPSLAMWLVNGFQLLYVGDALWYEESVLTTMDIIHDGFGFMLVFGDLAWVPFTYSLQAQFLLYHPQPLGLPMALLICLLKVIGYYIFRGANSQKNTFRKNPSDPSVAGLETIPTATGRQLLVSGWWGMVRHPNYLGDLIMALAWSLPCGLSHLLPYFYVLYFTALLVHREARDEQQCLQKYGRAWQEYCKRVPYRIIPYVY","proteome":"UP000000589","gene":"Tm7sf2","go_terms":[{"identifier":"GO:0016628","name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016126","name":"sterol biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"9a69035bc8c6d4031bf06ea0caf3992496028c64","counters":{"domain_architectures":10044,"entries":7,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"panther":1,"pfam":1,"prosite":2,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":10044}}}