{"metadata":{"accession":"Q6NYK1","id":"Q6NYK1_DANRE","source_organism":{"taxId":"7955","scientificName":"Danio rerio","fullName":"Danio rerio (Zebrafish)"},"name":"Deoxyhypusine synthase","description":["Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function"],"length":361,"sequence":"MAGQAPPVARAAVLKESTPLPDNLPQIRGYDFNQGLNHRALLQSFITTGFQASSFGLAVQEINKMIEKRLEPVQEECEDSDSRQSALGCTIFLGYTSNLISSGVRESIRYLTQHKMVDVIVTTAGGIEEDLIKCLAPTFLGEFSLKGKELRQQGINRIGNLLVPNENYCKFEDWLMPILDQMVLEQKTEGTHWTPSKMIHRLGKEINNPDSVYYWAYKNDIPVFSPALTDGSLGDMIYFHSYKNPGLVLDIVEDIRRLNSKAVFAKSTGMIILGGGLVKHHIANANLMRNGADFAVFVNTGQEFDGSDSGARPDEAISWGKIRMDASPVKVYADASLVFPLLVAETFAHNASRLIQEKKSD","proteome":"UP000000437","gene":"dhps","go_terms":[{"identifier":"GO:0008612","name":"peptidyl-lysine modification to peptidyl-hypusine","category":{"code":"P","name":"biological_process"}}],"protein_evidence":1,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"0c9d7e372bf375b99409cae5c1de08d312149675","counters":{"domain_architectures":10021,"entries":8,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"pfam":1,"panther":1,"ncbifam":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":10021}}}