{"metadata":{"accession":"Q5U560","id":"THP1A_XENLA","source_organism":{"taxId":"8355","scientificName":"Xenopus laevis","fullName":"Xenopus laevis (African clawed frog)"},"name":"THAP domain-containing protein 1 A","description":["DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes (By similarity)"],"length":225,"sequence":"MVQSCSAYGCKNRYDKDKPISFHKFPLKRPLLCKKWEAAVRRAEFKPTKYSSICSDHFSADCFKRECNNKLLKDNAVPTIFAHMEIKKKSGKAVKKEQLPAEPEPVPAVPEIDPAIGLLLPPLYTPSHIAVICDHNYTVEDTVHQRRRIQQLEEQVDKLRKKLKIANQKCRRQERSLEKLEREVSEYREAKGSGYVIFPGNYYEVLNENEYKELTPEITYKEIIL","proteome":"UP000186698","gene":"thap1-a","go_terms":[{"identifier":"GO:0043565","name":"sequence-specific DNA binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":2,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"d0643f96eba1dfa30941482fd5309ac69166bce7","counters":{"domain_architectures":21492,"entries":10,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"profile":1,"ssf":1,"smart":2,"pfam":1,"cathgene3d":1,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":21492}}}