{"metadata":{"accession":"Q5E6Y5","id":"THII_ALIF1","source_organism":{"taxId":"312309","scientificName":"Aliivibrio fischeri (strain ATCC 700601 / ES114)","fullName":"Aliivibrio fischeri (strain ATCC 700601 / ES114)"},"name":"tRNA sulfurtransferase","description":["Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS"],"length":482,"sequence":"MKFIVKPHPEVFVKSDSVRKRFIRILESNLRSIIQRETKGVEVINRRDHIEVTGLSDEYRDVTLAVLTQTPGIHHVLEVKQSGFKDMHDIFEQCLEMNREVIEGKTFCVRVKRRGNHDFTSIELERYVGGGLNQSVESASVRLKNPEVTVKFEVANDKLNLIIARHKGLGGFPLGTQEDVLSLISGGFDSGVSSYLHIKRGSKVHYLFFNLGGPAHEIGVKQVSHFLWKKYGSSAKVKFISVDFDPVVAEILEKVDDGQMGVILKRMFMRAGGMVAEKFGIEGLVTGEALGQVSSQTLTNLRHIDNVTDSLILRPLINWDKEDIIDLAREIGTEDFAKTMPEYCGVISKKPTVKAVKEKLEKEEAKFDFSVLEQAVYNARVMDIRDIEKESQEQAPEVEMVSELGSDVVVLDIRSAEEEDEKPLELDGVEVTHIPFFKLATKFGDLDQSKEYLLYCERGVMSRLQALLLIENGYKNVKVYRP","proteome":"UP000000537","gene":"thiI","go_terms":[{"identifier":"GO:0003723","name":"RNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004810","name":"CCA tRNA nucleotidyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016783","name":"sulfurtransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0034227","name":"tRNA thio-modification","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0052837","name":"thiazole biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"ea3f690e6185778d45aa1a0cb700c6ecf442026d","counters":{"domain_architectures":272,"entries":28,"isoforms":0,"proteomes":1,"sets":5,"structures":0,"taxa":1,"dbEntries":{"ssf":3,"cathgene3d":3,"cdd":3,"profile":2,"smart":1,"pfam":2,"panther":1,"hamap":1,"ncbifam":2,"interpro":10},"proteome":1,"taxonomy":1,"similar_proteins":272}}}