{"metadata":{"accession":"Q5A5Q6","id":"ASH1_CANAL","source_organism":{"taxId":"237561","scientificName":"Candida albicans (strain SC5314 / ATCC MYA-2876)","fullName":"Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)"},"name":"Transcriptional regulatory protein ASH1","description":["Component of the RPD3C(L) histone deacetylase complex (HDAC). Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity). Controls filamentous growth and required for full virulence in a mouse model of disseminated candidiasis"],"length":449,"sequence":"MSLVQSAMFNHHMGPSHTRSRSFELFQEAKTLRVAACKRSYSDDLNISTKRARTAPPSPPYETATPTRASRLVISNLVKPTSNLRSRSLSPNKKFSSPLSPSSSPIATVTSPISSPQNIKIKLPSISDALNLPPITSKEPVKLKPIVPTVSLDYFDTYKPNDENWRYGLLDKIAKESKHFHLNQYNYLNDHAKPSFDSKLSSKIQQSSIANGKKINFPYESNYTYLNKTYLNDVKNYPEYLELAAESLLQLKERQLPPPPLQSHQKQHPPPPPHLPVQGLLPVPAPPVSHFSSSYTTPQAPTFYHPPSQQQQQTPPPQTLHHQQPQPPISTHKFIPISPPSAKKSRSDLLKSPPKHHHHHAPRVCISCGSDQSPCWRPSWSIKQGQLCNSCGLRYKKTKARCLNDKCKKIPAKGEWTLMQSKGKETFEDGIEGYSCIACGWRVEVLPKS","proteome":"UP000000559","gene":"ASH1","go_terms":[{"identifier":"GO:0008270","name":"zinc ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006355","name":"regulation of DNA-templated transcription","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0043565","name":"sequence-specific DNA binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":2,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"3e4e9e6a0662cb18564193c584fc8c907508990e","counters":{"domain_architectures":21748,"entries":8,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"profile":1,"smart":1,"ssf":1,"cdd":1,"pfam":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":21748}}}