{"metadata":{"accession":"Q54LQ6","id":"ITPA_DICDI","source_organism":{"taxId":"44689","scientificName":"Dictyostelium discoideum","fullName":"Dictyostelium discoideum (Social amoeba)"},"name":"Inosine triphosphate pyrophosphatase","description":["Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions"],"length":194,"sequence":"MSISKKIVFVTGNAKKLEEALQILGTSFPIESKKVDLPELQGDPIDISIEKCKIAAREVGGPVLVEDTCLCFNALKGLPGPYVKWFLDKLEPEGLYKLLDAWEDKSAYALCNFAFSEGPDSEPIVFAGKTDGIIVQPRGPRNFGWDPVFQPDGYKETYAEMDKSIKNTISHRTRSLQKVKEFLKSKGYENCKFE","proteome":"UP000002195","gene":"itpa","go_terms":[{"identifier":"GO:0047429","name":"nucleoside triphosphate diphosphatase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009143","name":"nucleoside triphosphate catabolic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"029a777975285995c6aff1e90978714c8929fb21","counters":{"domain_architectures":32111,"entries":9,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":1,"cdd":1,"hamap":1,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":32111}}}