{"metadata":{"accession":"Q54823","id":"DNRQ_STRPE","source_organism":{"taxId":"1950","scientificName":"Streptomyces peucetius","fullName":"Streptomyces peucetius"},"name":"Anthracycline biosynthesis protein DnrQ","description":["Involved in the biosynthesis of the anthracyclines carminomycin and daunorubicin (daunomycin) which are aromatic polyketide antibiotics that exhibit high cytotoxicity and are widely applied in the chemotherapy of a variety of cancers. DnrQ is required for the glycosylation of epsilon-rhodomycinone by DnrS to yield rhodomycin D"],"length":438,"sequence":"MPTPTSAPPAAPTDSELGRHLLTVRGFHFVFGALGDPYARRLRGEADHLSLGELVRDRGPLHGSALGTWVTADGGISARLLDDPLLGPRHPASEGPQEHVLENVWETWRTCHVTPLGEDLLTPAAADSDRLAALLGPVLGPRTCTAWQVDAGRAVHRVLDGLPPHFDVVSDLARPAIAGSLAAVLGLPDEARAELPDLLAACGPVLDSALCPPRLPVARAMTQALRRVRELMAAAVANHLTAPADGAVSALLAVDPGGGRDPGDTVTAAVLSTVVGAETAITTVANAVMALLKHDEQWSLLRADPGRAADAVEETLRWAPPVTLRSLITQGEVQIGGETLEADQHVVVLVDAAQRDPALYEDPDRFRLDRPRSPGFTHMALAGRDHLGLVAPLVRVQCTAVLRALAERLPGLRAEGEPLRRGRSPVVRAPLSLRLAQK","proteome":null,"gene":"dnrQ","go_terms":[{"identifier":"GO:0004497","name":"monooxygenase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005506","name":"iron ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016705","name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0020037","name":"heme binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"a02e61ba6c64bb9a9c779746e03a6c43264a16fb","counters":{"domain_architectures":520850,"entries":11,"isoforms":0,"proteomes":0,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"cdd":1,"pfam":1,"ncbifam":1,"panther":1,"prints":1,"interpro":4},"proteome":0,"taxonomy":1,"similar_proteins":520850}}}