{"metadata":{"accession":"Q543T6","id":"Q543T6_MOUSE","source_organism":{"taxId":"10090","scientificName":"Mus musculus","fullName":"Mus musculus (Mouse)"},"name":"Gamma-tubulin complex component","description":["Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation"],"length":667,"sequence":"MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIEQYTGHVQQQDHHPPQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLADPHLSISHVNYSLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCHGVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGTLSAQLEEDEEDLGIGGLTGKQLRELQDLRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQNVNLTRKGSILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEYHGKDHKADATQPREVPSRETSPREAPSSGWAALGLSYKVQWPLHILFTPAVLEKYNVVFKYLLSVRRVQAELQHCWALQMQRKHLKSNQTDAVKWRLRNHMAFLVDNLQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLKPVFHCLNEILDLCHSFCSLVSQNLGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGGTLGSFGM","proteome":null,"gene":"Tubgcp4","go_terms":[{"identifier":"GO:0043015","name":"gamma-tubulin binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000226","name":"microtubule cytoskeleton organization","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0007020","name":"microtubule nucleation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0000922","name":"spindle pole","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0005815","name":"microtubule organizing center","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":1,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"1410925767f37438da28a96a312811fe4b2df3f4","counters":{"domain_architectures":17307,"entries":8,"isoforms":0,"proteomes":0,"sets":1,"structures":0,"taxa":1,"dbEntries":{"pfam":2,"cathgene3d":1,"panther":1,"interpro":4},"proteome":0,"taxonomy":1,"similar_proteins":17307}}}