{"metadata":{"accession":"Q3Z6U4","id":"ISPH_DEHM1","source_organism":{"taxId":"243164","scientificName":"Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195)","fullName":"Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195)"},"name":"4-hydroxy-3-methylbut-2-enyl diphosphate reductase","description":["Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis"],"length":284,"sequence":"MKVECASNIGFCFGVRRAINILEKTAAEKGGVETLGALVHNQQVLNRLSGMGVRVVKNIEDISGRTVAISSHGVGPLVLDELKSKGLEVVDTTCPFVKRAQVAAKRFHDAGFFTVIYGDVNHPEVKGIMGWAGGDGLATLNPQGLVDVPDVSRYIGVLSQTTQIPTGFTSFVKNVIDQALVKDAEIRIADTLCHDIRERQTAALELAGRVDLMLVIGGHNSANTRHLLDLCKTVSNTYLIETASELQTGWLRGVNRIGITSGASTDETTISEVCSYLGSLSAGT","proteome":"UP000008289","gene":"ispH","go_terms":[{"identifier":"GO:0046872","name":"metal ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0051745","name":"4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0019288","name":"isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0050992","name":"dimethylallyl diphosphate biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"fcbea5256286b22a5f6231f48f5b4e45375830bf","counters":{"domain_architectures":23559,"entries":8,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cdd":1,"cathgene3d":2,"panther":1,"hamap":1,"ncbifam":1,"pfam":1,"interpro":1},"proteome":1,"taxonomy":1,"similar_proteins":23559}}}