{"metadata":{"accession":"P69933","id":"HDA_ECO57","source_organism":{"taxId":"83334","scientificName":"Escherichia coli O157:H7","fullName":"Escherichia coli O157:H7"},"name":"DnaA regulatory inactivator Hda","description":["Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity)"],"length":233,"sequence":"MNTPAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL","proteome":"UP000000558","gene":"hda","go_terms":[{"identifier":"GO:0032297","name":"negative regulation of DNA-templated DNA replication initiation","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"44032ada816e1f9e3432afe50b91752cf7856a7d","counters":{"domain_architectures":3960,"entries":16,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"pfam":2,"ssf":1,"ncbifam":2,"hamap":1,"panther":1,"prints":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":3960}}}