{"metadata":{"accession":"P62895","id":"CYC_PIG","source_organism":{"taxId":"9823","scientificName":"Sus scrofa","fullName":"Sus scrofa (Pig)"},"name":"Cytochrome c","description":["Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain","Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity)"],"length":105,"sequence":"MGDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGFSYTDANKNKGITWGEETLMEYLENPKKYIPGTKMIFAGIKKKGEREDLIAYLKKATNE","proteome":"UP000008227","gene":"CYCS","go_terms":[{"identifier":"GO:0009055","name":"electron transfer activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0020037","name":"heme binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"190ccab1ff44fe1a3b1be561b80e69bb85fa539b","counters":{"domain_architectures":48058,"entries":9,"isoforms":0,"proteomes":1,"sets":1,"structures":1,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"profile":1,"pfam":1,"panther":1,"prints":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":48058}}}