{"metadata":{"accession":"P59637","id":"VEMP_SARS","source_organism":{"taxId":"694009","scientificName":"Severe acute respiratory syndrome coronavirus","fullName":"Severe acute respiratory syndrome coronavirus (SARS-CoV)"},"name":"Envelope small membrane protein","description":["Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis (By similarity). Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction"],"length":76,"sequence":"MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNIVNVSLVKPTVYVYSRVKNLNSSEGVPDLLV","proteome":"UP000000354","gene":"E","go_terms":[{"identifier":"GO:0019068","name":"virion assembly","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0046760","name":"viral budding from Golgi membrane","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":false,"in_bfvd":false,"ida_accession":"fe089b24b8342db75b5f45561e57c179de583659","counters":{"domain_architectures":981,"entries":8,"isoforms":0,"proteomes":1,"sets":1,"structures":5,"taxa":1,"dbEntries":{"profile":1,"cdd":1,"cathgene3d":1,"hamap":1,"pfam":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":981}}}