{"metadata":{"accession":"P48965","id":"MPIP1_RAT","source_organism":{"taxId":"10116","scientificName":"Rattus norvegicus","fullName":"Rattus norvegicus (Rat)"},"name":"M-phase inducer phosphatase 1","description":["Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression (PubMed:10373478). Directly dephosphorylates CDK1 and stimulates its kinase activity (PubMed:10373478). Also dephosphorylates CDK2 in complex with cyclin-E, in vitro (By similarity)"],"length":525,"sequence":"MELGPEPPHRRRLLFTCSPTPAPQPTGKVQFGASRAGGLSPVTNLTVTMDQLEGLGSDYEKPMDVRNSSSLQRMGSSESTDSGFCLDSPGPLDSKENLEISLRRINCLPQKLLGCSPALKRSHSDSLDHDIFQLIDQDENKENEAFEFKKPIRPASRGCLNAHVHEESKDPFTHRQNSAPARMLSSNESDISESGNFSPLFTPQSPVKASLSDEDDGFIDLLDGENLKNDEETPSCMSSLWTAPLVMRRPTNLADRCGLFDSPSPCSSTSSCSTRAVKRADRSHEESPRGTKRRKSSEASPVKADVPEPTQLPHQSLSLTSFPKGTIENIFHSDPRDLIGDFSKGYLFHTVSGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEEFLLKKPIVPADGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFLKCQSHCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL","proteome":"UP000002494","gene":"Cdc25a","go_terms":[{"identifier":"GO:0004725","name":"protein tyrosine phosphatase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006470","name":"protein dephosphorylation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:1902751","name":"positive regulation of cell cycle G2/M phase transition","category":{"code":"P","name":"biological_process"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"6bed4c2dd544b4e3d3ce2c29ca7ca19e33599cb6","counters":{"domain_architectures":2057,"entries":12,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"cdd":1,"smart":1,"pfam":2,"profile":1,"panther":1,"prints":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":2057}}}