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InterPro-Version: 110.0
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{
"metadata": {
"accession": "P30878",
"id": "MELB_SALTY",
"source_organism": {
"taxId": "99287",
"scientificName": "Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)",
"fullName": "Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)"
},
"name": "Melibiose permease",
"description": [
"Mediates the transport of melibiose and other galactosides by a symport mechanism (PubMed:21148559, PubMed:24389923, PubMed:29054867, PubMed:34110360). Can use sodium, lithium and protons as coupling cations, with a preference for sodium and lithium (PubMed:21148559, PubMed:24389923, PubMed:29054867). The use of Na(+) as coupling ion for sugar transport is based not on ion selectivity but on competitive binding under physiological conditions, because of a much higher Na(+) concentration under physiological conditions (PubMed:29054867)"
],
"length": 476,
"sequence": "MSISLTTKLSYGFGAFGKDFAIGIVYMYLMYYYTDVVGLSVGLVGTLFLVARIWDAINDPIMGWIVNATRSRWGKFKPWILIGTLTNSLVLFLLFSAHLFEGTAQVVFVCVTYILWGMTYTIMDIPFWSLVPTITLDKREREQLVPFPRFFASLAGFVTAGITLPFVSYVGGADRGFGFQMFTLVLIAFFIASTIVTLRNVHEVYSSDNGVTAGRPHLTLKTIVGLIYKNDQLSCLLGMALAYNIASNIINGFAIYYFTYVIGDADLFPYYLSYAGAANLLTLIVFPRLVKMLSRRILWAGASVMPVLSCAGLFAMALADIHNAALIVAAGIFLNIGTALFWVLQVIMVADTVDYGEFKLNIRCESIAYSVQTMVVKGGSAFAAFFIALVLGLIGYTPNVAQSAQTLQGMQFIMIVLPVLFFMMTLVLYFRYYRLNGDMLRKIQIHLLDKYRKTPPFVEQPDSPAISVVATSDVKA",
"proteome": "UP000001014",
"gene": "melB",
"go_terms": [
{
"identifier": "GO:0015293",
"name": "symporter activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0008643",
"name": "carbohydrate transport",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0016020",
"name": "membrane",
"category": {
"code": "C",
"name": "cellular_component"
}
},
{
"identifier": "GO:0006814",
"name": "sodium ion transport",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0022857",
"name": "transmembrane transporter activity",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 1,
"source_database": "reviewed",
"is_fragment": false,
"in_alphafold": true,
"ida_accession": "18700fec056a4a6b8afdaf19377d37db5df6a411",
"counters": {
"domain_architectures": 27949,
"entries": 12,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 10,
"taxa": 1,
"dbEntries": {
"cdd": 1,
"cathgene3d": 1,
"ssf": 1,
"ncbifam": 2,
"panther": 1,
"pfam": 1,
"prosite": 1,
"interpro": 4
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 27949
}
}
}