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{
    "metadata": {
        "accession": "P28741",
        "id": "KIF3A_MOUSE",
        "source_organism": {
            "taxId": "10090",
            "scientificName": "Mus musculus",
            "fullName": "Mus musculus (Mouse)"
        },
        "name": "Kinesin-like protein KIF3A",
        "description": [
            "Microtubule-based anterograde translocator for membranous organelles, such as primary cilium and centriole (PubMed:18497258, PubMed:21670265, PubMed:23386061, PubMed:7559760). Shows a plus end-directed microtubule sliding activity in vitro (PubMed:7559760). Plays a role in primary cilia formation, probably by mediating transport of proteins into primary cilia (PubMed:18497258, PubMed:21670265, PubMed:39138140). Mediates smoothened (SMO) translocation into primary cilia in response to hedgehog morphogens (PubMed:18497258, PubMed:39138140). Plays a role in centriole cohesion and subdistal appendage organization and function (PubMed:23386061). Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole (PubMed:23386061). Also required for ciliary basal feet formation and microtubule anchoring to mother centriole (PubMed:23386061)"
        ],
        "length": 701,
        "sequence": "MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYRQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAVPGLRGVIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEVSGSDISGSEEDDEEGELGEDGEKKKKRRDQAGKKKVSPDKMVEMQAKIDEERKALETKLDMEEEERNKARAELERREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRRRAEQLRKELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPQDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKERDPFEVDLSHVYLAYTEESLRQSLMKLERPRTSKGKARPKMGRRKRSAKPETVIDSLLQ",
        "proteome": "UP000000589",
        "gene": "Kif3a",
        "go_terms": [
            {
                "identifier": "GO:0003777",
                "name": "microtubule motor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005524",
                "name": "ATP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0008017",
                "name": "microtubule binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0007018",
                "name": "microtubule-based movement",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 1,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "ida_accession": "f01ad1f8bd2f963f0b0c11ced3ae1308131d5877",
        "counters": {
            "domain_architectures": 74955,
            "entries": 14,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 4,
            "taxa": 1,
            "dbEntries": {
                "smart": 1,
                "cdd": 1,
                "cathgene3d": 1,
                "profile": 1,
                "ssf": 1,
                "pfam": 1,
                "panther": 1,
                "prosite": 1,
                "prints": 1,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 74955
        }
    }
}