{"metadata":{"accession":"P09167","id":"AERA_AERHY","source_organism":{"taxId":"644","scientificName":"Aeromonas hydrophila","fullName":"Aeromonas hydrophila"},"name":"Aerolysin","description":["Secreted, cytolytic toxin that forms pores in host membranes after proteolytic removal of a C-terminal propeptide, leading to destruction of the membrane permeability barrier and host cell death. The pores are formed by transmembrane beta-strands and are approximately 3 nm in diameter"],"length":493,"sequence":"MQKIKLTGLSLIISGLLMAQAQAAEPVYPDQLRLFSLGQGVCGDKYRPVNREEAQSVKSNIVGMMGQWQISGLANGWVIMGPGYNGEIKPGTASNTWCYPTNPVTGEIPTLSALDIPDGDEVDVQWRLVHDSANFIKPTSYLAHYLGYAWVGGNHSQYVGEDMDVTRDGDGWVIRGNNDGGCDGYRCGDKTAIKVSNFAYNLDPDSFKHGDVTQSDRQLVKTVVGWAVNDSDTPQSGYDVTLRYDTATNWSKTNTYGLSEKVTTKNKFKWPLVGETELSIEIAANQSWASQNGGSTTTSLSQSVRPTVPARSKIPVKIELYKADISYPYEFKADVSYDLTLSGFLRWGGNAWYTHPDNRPNWNHTFVIGPYKDKASSIRYQWDKRYIPGEVKWWDWNWTIQQNGLSTMQNNLARVLRPVRAGITGDFSAESQFAGNIEIGAPVPLAADSKVRRARSVDGAGQGLRLEIPLDAQELSGLGFNNVSLSVTPAANQ","proteome":null,"gene":"aerA","go_terms":[{"identifier":"GO:0005576","name":"extracellular region","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"2af55c5be9c0c036b09e4099c82795e476a8351e","counters":{"domain_architectures":229,"entries":17,"isoforms":0,"proteomes":0,"sets":3,"structures":17,"taxa":1,"dbEntries":{"pfam":2,"cathgene3d":3,"ssf":2,"smart":1,"cdd":1,"prints":1,"prosite":1,"interpro":6},"proteome":0,"taxonomy":1,"similar_proteins":229}}}