"accession"	"counters"	"description"	"gene"	"go_terms"	"id"	"ida_accession"	"in_alphafold"	"in_bfvd"	"is_fragment"	"length"	"name"	"protein_evidence"	"proteome"	"sequence"	"source_database"	"source_organism"
"P00959"	"{'domain_architectures': 13265, 'entries': 34, 'isoforms': 0, 'proteomes': 1, 'sets': 6, 'structures': 24, 'taxa': 1, 'dbEntries': {'ssf': 4, 'cdd': 3, 'cathgene3d': 4, 'pfam': 3, 'profile': 1, 'panther': 1, 'ncbifam': 3, 'hamap': 1, 'prosite': 1, 'prints': 1, 'interpro': 12}, 'proteome': 1, 'taxonomy': 1, 'similar_proteins': 13265}"	"['Catalyzes the attachment of L-methionine to tRNA(Met) (PubMed:216545, PubMed:367445, PubMed:4297674, PubMed:4581817, PubMed:7932711). Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (PubMed:216545, PubMed:4581817). MetRS can indeed attach methionine to tRNA(mMet), which supplies methionine for elongation of nascent peptides, and to tRNA(fMet), which supplies formylmethionine for initiation of peptide synthesis (PubMed:216545, PubMed:4581817). However, MetRS charges tRNA(fMet) with a greater efficiency than tRNA(mMet) in several strains of E.coli, suggesting a preference for initiation of new peptides (PubMed:216545). Cannot use D-methionine (PubMed:4297674)', 'In addition, MetRS can reject misactivated homocysteine by a tRNA-independent hydrolysis of the homocysteinyl-AMP intermediate, preventing incorporation of homocysteine into tRNA and proteins (PubMed:2191291, PubMed:7024910). The homocysteinyl-AMP intermediate undergoes an intramolecular cyclization reaction in which the thiolate side chain of homocysteine displaces the AMP group, forming homocysteine-thiolactone and AMP (PubMed:2191291, PubMed:7024910)']"	"metG"	"[{'identifier': 'GO:0004825', 'name': 'methionine-tRNA ligase activity', 'category': {'code': 'F', 'name': 'molecular_function'}}, {'identifier': 'GO:0006431', 'name': 'methionyl-tRNA aminoacylation', 'category': {'code': 'P', 'name': 'biological_process'}}, {'identifier': 'GO:0000166', 'name': 'nucleotide binding', 'category': {'code': 'F', 'name': 'molecular_function'}}, {'identifier': 'GO:0004812', 'name': 'aminoacyl-tRNA ligase activity', 'category': {'code': 'F', 'name': 'molecular_function'}}, {'identifier': 'GO:0005524', 'name': 'ATP binding', 'category': {'code': 'F', 'name': 'molecular_function'}}, {'identifier': 'GO:0006418', 'name': 'tRNA aminoacylation for protein translation', 'category': {'code': 'P', 'name': 'biological_process'}}, {'identifier': 'GO:0000049', 'name': 'tRNA binding', 'category': {'code': 'F', 'name': 'molecular_function'}}]"	"SYM_ECOLI"	"605e59fa9284a45ce9616dfe8a2213f70331198f"	True	False	False	677	"Methionine--tRNA ligase"	1	"UP000000625"	"MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPSNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMRQVEALVEASKEEVKAAAAPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK"	"reviewed"	"{'taxId': '83333', 'scientificName': 'Escherichia coli (strain K12)', 'fullName': 'Escherichia coli (strain K12)'}"