"accession"	"counters"	"description"	"gene"	"go_terms"	"id"	"ida_accession"	"in_alphafold"	"in_bfvd"	"is_fragment"	"length"	"name"	"protein_evidence"	"proteome"	"sequence"	"source_database"	"source_organism"
"O27661"	"{'domain_architectures': 2266, 'entries': 34, 'isoforms': 0, 'proteomes': 1, 'sets': 3, 'structures': 0, 'taxa': 1, 'dbEntries': {'smart': 3, 'profile': 2, 'cathgene3d': 5, 'ssf': 2, 'cdd': 1, 'pfam': 3, 'panther': 1, 'hamap': 1, 'ncbifam': 1, 'prints': 1, 'prosite': 1, 'interpro': 13}, 'proteome': 1, 'taxonomy': 1, 'similar_proteins': 2266}"	"[""Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone""]"	"topA"	"[{'identifier': 'GO:0003677', 'name': 'DNA binding', 'category': {'code': 'F', 'name': 'molecular_function'}}, {'identifier': 'GO:0003916', 'name': 'DNA topoisomerase activity', 'category': {'code': 'F', 'name': 'molecular_function'}}, {'identifier': 'GO:0006265', 'name': 'DNA topological change', 'category': {'code': 'P', 'name': 'biological_process'}}, {'identifier': 'GO:0005694', 'name': 'chromosome', 'category': {'code': 'C', 'name': 'cellular_component'}}, {'identifier': 'GO:0003917', 'name': 'DNA topoisomerase type I (single strand cut, ATP-independent) activity', 'category': {'code': 'F', 'name': 'molecular_function'}}]"	"TOP1_METTH"	"11c2314b289f96f2d423a6c34998a980f58fa56e"	True	False	False	718	"DNA topoisomerase 1"	3	"UP000005223"	"MRSLSGKMHEVIICEKPKSSEKIAGALFPDAMKKKHGKVSYWEHVEGDKRVTIVSAVGHLYSLRPRQSNEEHFFDLEWAPIHEIDKKKGYVKDYLNVIRKFAAGADRYIHACDYDIEGTLIGFNALKYGCGEEALRKTSRMKFSTLTREEIQRAYKNPIEVDYGQVDSGAARHILDFIFGVNISRSLMKSVKAATNRFIKLSAGRVQTPTLAILVEREKEIRDFKPVPYWIIRAELGEGIIAESKRGKIFKRELVDSILEKCQGSDAEVKDVRVRDTIRKPPVPFDLGTLQSEAYRVFGFSPKKTQTIAQNLYTEGYTSYPRTSSQKLPESIGYEKILKNLAKNPRFGVHIERLRGPLKPHEGKKEDDAHPAIHPTGLLPSELSKDEKKVYDLIVHRFISVFGEDAILQTMKVELEIGEEEFSFSRKRVSKAGWMESYPYTKMEDEEFPEISGGDSLAVRSVSADERETKPPARYNEASLIRELERRGLGTKSTRADIIAKLYDRKYIEGKKIRVSPLGENIIDTLTRYCEKIISEELTRQFERELEDIMRGKISKDRVIDEAITEVRSILSDIEENLRDIGKELYRAYQDSRVVGECPACGGKLVIKYSPRNRSTFVGCSSYPDCRTVYSLPRGASVLKSLCEKCGLPMISYGRPRQRACLDPKCGKKKSEVEEVVGKCPECGSDLIKRSGRYGEFVGCKGFPKCRFTCSVDEVPEG"	"reviewed"	"{'taxId': '187420', 'scientificName': 'Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)', 'fullName': 'Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)'}"