{"metadata":{"accession":"O06522","id":"CDTA_HAEDU","source_organism":{"taxId":"233412","scientificName":"Haemophilus ducreyi (strain 35000HP / ATCC 700724)","fullName":"Haemophilus ducreyi (strain 35000HP / ATCC 700724)"},"name":"Cytolethal distending toxin subunit A","description":["CDTs are cytotoxins which induce host cell distension, growth arrest in G2/M phase, nucleus swelling, and chromatin fragmentation in HeLa cells. CdtA, along with CdtC, probably forms a heterodimeric subunit required for the delivery of CdtB"],"length":223,"sequence":"MKKFLPSLLLMGSVACSSNQRMNDYSQPESQSDLAPKSSTIQPQPQPLLSKTPSMSLNLLSSSGPNRQVLPSEPSNFMTLMGQNGALLTVWALAKRNWLWAYPNIYSQDFGNIRNWKMEPGKHREYFRFVNQSLGTCVEAYGNGLIHDICSLDKLAQEFELLPTDSGAVVIKSVSQGRCVTYNPVSTTFYSTVTLSVCDGATEPSRDQTWYLAPPVLEATAVN","proteome":"UP000001022","gene":"cdtA","go_terms":null,"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"300f5d9bb6e158429d722a85f63f3f0b6bfb12fd","counters":{"domain_architectures":759,"entries":11,"isoforms":0,"proteomes":1,"sets":1,"structures":1,"taxa":1,"dbEntries":{"profile":2,"cathgene3d":1,"ssf":1,"cdd":1,"pfam":1,"pirsf":1,"prints":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":759}}}