{"metadata":{"accession":"M7BGN1","id":"M7BGN1_CHEMY","source_organism":{"taxId":"8469","scientificName":"Chelonia mydas","fullName":"Chelonia mydas (Green sea-turtle)"},"name":"Kynurenine--oxoglutarate transaminase 3","description":["Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro)"],"length":398,"sequence":"VEFTKVAADPSVVNLGQGLPDISPPSYVKEELAKAATVDKLNQYTRGFGHPLLVKALSQVYEKVCGRKIDPYTDVLVTVGGYGSLFSAIQGLIEAGDEVIIIEPFFDCYEPMVKMAGGKPVFIPLRYKTVIGNSASSADWVLDATELASKFNSRTKAILLNTPHNPIGKVFTKEELQVIADLCIKHDTLCFSDEVYEWLVYKGNKHIKIATLPGMWERTITIGSAGKTYSVTGWKLGWSIGPQHLIKHLQVVQQNTLYACPTPLQEALAQALWIDFKRMDDPDCYFYSLSRELEGKRNRMAQLLQEVGLKPVIPDGGYFMIVDVSALNVDLSDMEANQHYDYKFVKWMIKSKKLSAIPLTAFCGPDTKKQFEKYIRFCFIKQDSTLDAAEVILKNWNK","proteome":"UP000031443","gene":"UY3_15541","go_terms":[{"identifier":"GO:0030170","name":"pyridoxal phosphate binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009058","name":"biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":true,"in_alphafold":true,"in_bfvd":false,"ida_accession":"220d43766bfe69807874ea078bc783ea7854e968","counters":{"domain_architectures":344728,"entries":11,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"ssf":1,"pfam":1,"cdd":1,"panther":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":344728}}}