{"metadata":{"accession":"L7PI50","id":"L7PI50_9EURO","source_organism":{"taxId":"41725","scientificName":"Aspergillus aurantiobrunneus","fullName":"Aspergillus aurantiobrunneus"},"name":"DNA replication licensing factor MCM7","description":["Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity"],"length":205,"sequence":"AVQINAYTCDRCGSEMFQPVTTKQFLPMTECESNDCKENNTKGQLFLSTRASKFIPFQEVKIQEMADQVPVGHIPRTMTVNCSGNLTRQLNPGDLVDIAGIFLPTPYTGFRAIRAGLLTDTYLEAQHITQHKKSYNDIGMDSRTLRKIEQYQKSGNMYEYLSRSIAPEIYGHLDVKKALLLLLIGGVTKEMGDGMHIRGDINICL","proteome":null,"gene":"mcm7","go_terms":[{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003678","name":"DNA helicase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006270","name":"DNA replication initiation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0042555","name":"MCM complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":true,"in_alphafold":true,"in_bfvd":false,"ida_accession":"c4da101550b82c589ed0a28ad40713455d60288f","counters":{"domain_architectures":4804,"entries":15,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"smart":1,"pfam":2,"ssf":1,"cathgene3d":2,"profile":1,"panther":1,"prints":1,"interpro":6},"proteome":0,"taxonomy":1,"similar_proteins":4804}}}