{"metadata":{"accession":"I8QYK4","id":"I8QYK4_9THEO","source_organism":{"taxId":"880478","scientificName":"Thermoanaerobacter siderophilus SR4","fullName":"Thermoanaerobacter siderophilus SR4"},"name":"Adenylosuccinate synthetase","description":["Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP"],"length":426,"sequence":"MSTLVIVGTQWGDEGKGKITDYLAEKADVVVRYQGGNNAGHTVEKGGVQYKLHLIPSGILYPDKICIIGNGVVIDPASLIEEIENLEKQGVSIENLKISDRAHIVFPYHIRQDELEELAKGKNDLGTTRKGIGPCYMDKSERIGIRVCDLIKPKVLEEKLKRNIEKKNKLFRDLYGVEGFDFDEMYKKYLEYAEKIKPFVTDTTVLLYDLIKSGKKVLFEGAQGTLLDLDLGTYPYVTASHPIAGGVTVGAGIGPTMIDEVIGVVKAYTTRVGKGPFPTELFDENGDFLREKGHEYGTTTGRPRRCGWLDAVILKYSVRVSGITHFALTKLDTLTGLKKIKICTGYRFKGEIITDFPASLEDLAQCEPVYEEFDGWEEDIQGAKTFDDLPYNAQKYIKRIEELIGIKAAIISVGPERNQTIVLRDF","proteome":"UP000005110","gene":"purA","go_terms":[{"identifier":"GO:0000166","name":"nucleotide binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004019","name":"adenylosuccinate synthase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006164","name":"purine nucleotide biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005525","name":"GTP binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"37cd307e3eb176206c7f16cb37bf0a0b66a13b7b","counters":{"domain_architectures":35081,"entries":21,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cdd":1,"smart":1,"cathgene3d":3,"pfam":1,"ncbifam":3,"hamap":1,"panther":1,"prosite":2,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":35081}}}