{"metadata":{"accession":"I3JUI1","id":"I3JUI1_ORENI","source_organism":{"taxId":"8128","scientificName":"Oreochromis niloticus","fullName":"Oreochromis niloticus (Nile tilapia)"},"name":"Transcription factor ETV6","description":["Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation"],"length":492,"sequence":"MCRVSKFPEITEEDCFLANSENPKDVKQERSSFSPSANPLPNSTSSPVHAPAARPASRMEDEPARLPAHLRLQPVFWSRDDVAQWLRWAEKEFALRPITSGSFQMNGKALLLLTKEDFRYRSPHSGDVLYELLQHILKQRKSHVFYPSAYFPGNSFHSLPESAVQHLKLEETVRRGPRGTEPIPQHPPTIELRHRSRSPHHPAPRRSPTEPNHPRPANEDSLQTFSQLPDSNHHLPEEMYPLSVSPAAPNGRCATPREAPCPGSPGGQEAGPPRVIQLMPSAIMNPLLLSPNRSGGAAGMDFRHNRGGPLSQVTLENGREGKVHGHHHQLAQQHQQQQQQQQQQLLQQQQEEALYRNHVIMPVSPPEEQQMPIGRIADCRLLWDYVYQLLSDSRYENYIRWEDPENKVFRIMDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLFRFMKTPDEIMNGQTDRLEHLESDTDEQIYIKEEC","proteome":"UP000005207","gene":"ETV6","go_terms":[{"identifier":"GO:0043565","name":"sequence-specific DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003700","name":"DNA-binding transcription factor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006355","name":"regulation of DNA-templated transcription","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0006357","name":"regulation of transcription by RNA polymerase II","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"522927238307a85066168b858327df5283cc4088","counters":{"domain_architectures":10817,"entries":20,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"smart":2,"profile":2,"cathgene3d":2,"pfam":2,"cdd":1,"panther":1,"prints":1,"prosite":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":10817}}}