{"metadata":{"accession":"H3ZM41","id":"H3ZM41_THELN","source_organism":{"taxId":"523849","scientificName":"Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C)","fullName":"Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C)"},"name":"tRNA-splicing endonuclease","description":["Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp"],"length":170,"sequence":"MSEFKFYLSGDRVFSTMESAINKLYNKRHYGEVVNGKLFLSLIEAAYLLDKGWIKVFDGEKELRVQELFEIGRKKDEQFDLKFLVYRDLRNRGYTVKTALKYGSHFRVYRKGMEEHADWLIWVVSENQKMYPNDLTARVRVAHGVRKKMVLAVVDEDNDVVYYHIGRIKF","proteome":"UP000015502","gene":"endA","go_terms":[{"identifier":"GO:0000213","name":"tRNA-intron lyase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006388","name":"tRNA splicing, via endonucleolytic cleavage and ligation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0003676","name":"nucleic acid binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"941abee8bd23336a20187cbb8cd57119e9ef0738","counters":{"domain_architectures":2064,"entries":18,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"pfam":2,"cathgene3d":2,"cdd":1,"hamap":1,"pirsf":1,"ncbifam":1,"panther":1,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":2064}}}