{"metadata":{"accession":"H3A144","id":"H3A144_LATCH","source_organism":{"taxId":"7897","scientificName":"Latimeria chalumnae","fullName":"Latimeria chalumnae (Coelacanth)"},"name":"Long-chain specific acyl-CoA dehydrogenase, mitochondrial","description":["Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, long-chain specific acyl-CoA dehydrogenase can act on saturated and unsaturated acyl-CoAs with 6 to 24 carbons with a preference for 8 to 18 carbons long primary chains"],"length":448,"sequence":"MATTVFSKTSVYDRVGLLIKYIYRFPAAASGTLTKVRYQYSQAREDQSQNAFRPETCISKSLMDIGTRRIFSEEHDIFRRSVRKFFQEEVVPYHSEWEKAGQVSRELWEKAGQQGLLGVNTAEEHGGIGGDLLSADVVWEEQAYVNCTGPGFSLHSDIVIPYITHYGSKSQIERYVPDMVAGKCIGAIAMTEPGAGSDLQGIRTYAKKDGSDWILNGSKVFITNGWMSDLVIVVAVTNREAKSAAHGISLFLVDNGMKGFIKGRKLDKIGLKAQDTAELFFEDVRLPAEALLGEVNKGFYYLMNELPQERLVVASFAISSCEFMFEETRNYVKERKAFGKTLAHLQTVQHKLAELKTQIYVGRVFFDSCLQLHAEKRLDSATASMAKYWASDLQNSVATQCVQLHGGWGYMWEYPIAKAFVDSRVQPIYGGSNEIMKELIARTIVRDN","proteome":"UP000008672","gene":"ACADL","go_terms":[{"identifier":"GO:0016627","name":"oxidoreductase activity, acting on the CH-CH group of donors","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0050660","name":"flavin adenine dinucleotide binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004466","name":"long-chain fatty acyl-CoA dehydrogenase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0042758","name":"long-chain fatty acid catabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0003995","name":"acyl-CoA dehydrogenase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"c9fd574aecd15169638af0612dc6d2bb4a1db62a","counters":{"domain_architectures":193077,"entries":21,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":3,"ssf":2,"pfam":3,"cdd":1,"panther":1,"prosite":2,"interpro":9},"proteome":1,"taxonomy":1,"similar_proteins":193077}}}