{"metadata":{"accession":"H2PJM6","id":"H2PJM6_PONAB","source_organism":{"taxId":"9601","scientificName":"Pongo abelii","fullName":"Pongo abelii (Sumatran orangutan)"},"name":"Interleukin-1 receptor-associated kinase 1-binding protein 1","description":["Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Acts by enhancing RELA transcriptional activity"],"length":279,"sequence":"MSLQKTPPTRVFVELVPWADRSRENNLVSGGETLPGLRHHLSSTQAQTATREVHVSGTSEVSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVENAYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPQFYHTPGSVENLRRQACLVAVENAWRKAQEVCNLVGQTLGKPLLIKEEETKEWEGQIDDHQSSRLSSSLTVQQKIKSATIHAASKVFITFEQLLESFFNIPTNNYSQIAMSPVNYHESHIK","proteome":"UP000001595","gene":"IRAK1BP1","go_terms":[{"identifier":"GO:0006955","name":"immune response","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0043123","name":"positive regulation of canonical NF-kappaB signal transduction","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"b0a347e8c5f642ecae602971bb04b3ddb37e6d30","counters":{"domain_architectures":22793,"entries":6,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"panther":1,"pfam":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":22793}}}