{"metadata":{"accession":"H0VS35","id":"H0VS35_CAVPO","source_organism":{"taxId":"10141","scientificName":"Cavia porcellus","fullName":"Cavia porcellus (Guinea pig)"},"name":"Single-stranded DNA binding protein Ssb-like OB fold domain-containing protein","description":["Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways"],"length":227,"sequence":"MRVREGLAMGYRGSGSMTTETFVKDIKPGLKNLNLIFIVLETGRVTKTKDGHEVRTCKVADKTGSINISVWDDVGNLIQPGDIIRLTKGYASVFKGCLTLYTGRGGDLQKIGEFCMVYSEVPNFSEPNPEYSTQQAPNKAGQNDSSPTATQAATGSSAVSPASESQNGNGLSTPPGPGGGSHPPHTPSHPPSTRITRSQPNHTAAGPPGSSSNPVSNGKETRRSSKR","proteome":"UP000005447","gene":"NABP2","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"b9921ba051ffc3e44a66b601d2df132d0be5617b","counters":{"domain_architectures":4583,"entries":8,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":1,"cdd":1,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":4583}}}