{"metadata":{"accession":"G9YL79","id":"G9YL79_FLAPL","source_organism":{"taxId":"411475","scientificName":"Flavonifractor plautii ATCC 29863","fullName":"Flavonifractor plautii ATCC 29863"},"name":"L-threonine dehydratase catabolic TdcB","description":["Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA"],"length":406,"sequence":"MLTLKEFKEARGVLSGVIRNTSLVYSPAFSKATGNQIYIKPENMQVTGAYKIRGAYYKISTLSDEEKARGLVTASAGNHAQGVAYAAQAAGVSATIVMPTTTPLVKVNNTKDYGAKVVLHGETFDDAAELAAKLSEEEGLTYVHPFNDPAIATGQGTISYEIFQDLPDVDVILVPIGGGGLATGVSTLAKLLNPNVTVIGVEPSGAASMKASLDAGHVVTLDRVETIADGVAVKTPGDQIFPYIQKNIDDIITIPDDELVDAFLDMMEKQKMIVENAGLLPIAALSHLKCRGKNVVPVLSGGNMDVITVASLVQHGLINRGRVFTFSVQLPDRPGELLRVAQLVAEANGNIIKLEHNQFVNINRQSGVELRVTLEAFGHTHKRAILDALCGAGYAARECHTNDFYH","proteome":null,"gene":"HMPREF0372_00242","go_terms":[{"identifier":"GO:0004794","name":"threonine deaminase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006567","name":"L-threonine catabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0030170","name":"pyridoxal phosphate binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006520","name":"amino acid metabolic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"8bc361cd7c1d6142f8798dedc919bc5496ed8194","counters":{"domain_architectures":181949,"entries":18,"isoforms":0,"proteomes":0,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cdd":2,"ssf":2,"cathgene3d":1,"profile":1,"pfam":1,"panther":1,"ncbifam":1,"prosite":1,"interpro":8},"proteome":0,"taxonomy":1,"similar_proteins":181949}}}