{"metadata":{"accession":"G9KN36","id":"G9KN36_MUSPF","source_organism":{"taxId":"9669","scientificName":"Mustela putorius furo","fullName":"Mustela putorius furo (European domestic ferret)"},"name":"Methionine-R-sulfoxide reductase B1","description":["Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages"],"length":94,"sequence":"MSFCSFSGGEIFQNHFEPGVYVCAKCGYELFSSRSKYAHSSPWPAFTETIHADSVAKRPERNSPDALKVSCGRCGNGLGHEFLNDGPKPGQSRF","proteome":null,"gene":null,"go_terms":[{"identifier":"GO:0033743","name":"peptide-methionine (R)-S-oxide reductase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":2,"source_database":"unreviewed","is_fragment":true,"in_alphafold":true,"in_bfvd":false,"ida_accession":"deb4c5e8efd21b1ddf07e78fdbd67304e03e4fcf","counters":{"domain_architectures":33949,"entries":8,"isoforms":0,"proteomes":0,"sets":1,"structures":0,"taxa":1,"dbEntries":{"profile":1,"ssf":1,"cathgene3d":1,"pfam":1,"panther":1,"interpro":3},"proteome":0,"taxonomy":1,"similar_proteins":33949}}}