{"metadata":{"accession":"G7WP42","id":"G7WP42_METH6","source_organism":{"taxId":"1110509","scientificName":"Methanothrix harundinacea (strain 6Ac)","fullName":"Methanothrix harundinacea (strain 6Ac)"},"name":"S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase","description":["Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe)"],"length":305,"sequence":"MSDQLKRQGYHLVAHGAVKPCLWLRRSIRGGDQCYKHHFYGISSHRCVQMTPTLLCNHRCLHCWRPIDEIPATSGEWIEPEELLDGILSEQRRLISGYGGAPETTDPGRLEEAKSPAHVAISLMGEPTLYPMIGELVEEVKRRGMTAFLVTNGTSPEAVGEVRPTQLYISLNAPDEETYRQVSNPRDDTWGRFLESLDMMRDSPSRRVVRLTLARNLNLKDPRGYARLIEVAEPDFVEVKAYMHLGLSRKRLGRDAMPTHDEVMGFARELSDILGYPLKNHVPLSRVALLSRGSAGEKIELGAGR","proteome":"UP000005877","gene":"taw1","go_terms":[{"identifier":"GO:0003824","name":"catalytic activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0051536","name":"iron-sulfur cluster binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016829","name":"lyase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0051539","name":"4 iron, 4 sulfur cluster binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008033","name":"tRNA processing","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"8f410f85842070b5c6f55e064c90b55a8cd35bca","counters":{"domain_architectures":1158,"entries":18,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"profile":1,"ssf":1,"pfam":2,"cdd":1,"hamap":1,"panther":1,"ncbifam":1,"sfld":3,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":1158}}}