{"metadata":{"accession":"G3VNE7","id":"G3VNE7_SARHA","source_organism":{"taxId":"9305","scientificName":"Sarcophilus harrisii","fullName":"Sarcophilus harrisii (Tasmanian devil)"},"name":"Glycine amidinotransferase","description":["Transamidinase that catalyzes the transfer of the amidino group of L-arginine onto the amino moiety of acceptor metabolites such as glycine, beta-alanine, gamma-aminobutyric acid (GABA) and taurine yielding the corresponding guanidine derivatives. Catalyzes the rate-limiting step of creatine biosynthesis, namely the transfer of the amidino group from L-arginine to glycine to generate guanidinoacetate, which is then methylated by GAMT to form creatine. Provides creatine as a source for ATP generation in tissues with high energy demands, in particular skeletal muscle, heart and brain"],"length":470,"sequence":"MAAPGEGREGGKLAYKAPREGGGSEARLLRAGGSGGPRCDSGAAALGKMLRVRCLRGGSRGAEAVHYIGSRIGRVFAGWVQRAFQSTQAAAASRNSFAAEDKATDPVPKDCPVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWPFYQQYGGQYFPKEHLKKAVAEIEEMCNILKMEGVTVKRPDPIDWSLKYKTPDFESTGLYGAMPRDILIVVGNEIIEAPMAWRARFFEYRAYRSIIKDYFHRGAKWTTAPKPTMANELYDQNYPIYSVEDRHKLAAQGKFVTTEYEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGLVLSNPDRPCHQIELFKKAGWTIVTPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGISTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYFD","proteome":"UP000007648","gene":"GATM","go_terms":[{"identifier":"GO:0015067","name":"amidinotransferase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":null,"counters":{"domain_architectures":0,"entries":5,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"cdd":1,"panther":1,"interpro":1},"proteome":1,"taxonomy":1}}}