{"metadata":{"accession":"G3SST7","id":"G3SST7_LOXAF","source_organism":{"taxId":"9785","scientificName":"Loxodonta africana","fullName":"Loxodonta africana (African elephant)"},"name":"D-aminoacyl-tRNA deacylase","description":["An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality"],"length":195,"sequence":"VGGEQISAIGRGLCVLLGISLEDTQKELEHMVRKILNLRVFEDESGKHWSKSVMDKEYEVLCVSQFTLQCVLKGNKPDFHLAMPTEQAEGFYNSFLEQLRKAYRPELIKDGEFSAYMQVHIQNDGPVTIELESPAAYAATSDPKQLSKLEKQQQRKEKTRAKGPSESSKERNVPRKEDRSASSGAEGDVSSEREP","proteome":"UP000007646","gene":"DTD1","go_terms":[{"identifier":"GO:0002161","name":"aminoacyl-tRNA deacylase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0051499","name":"D-aminoacyl-tRNA deacylase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005737","name":"cytoplasm","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"f5be7e64ef081c09c5a2f79246df4a2ddc956ba1","counters":{"domain_architectures":25258,"entries":8,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cdd":1,"cathgene3d":1,"pfam":1,"ncbifam":1,"panther":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":25258}}}