{"metadata":{"accession":"G3NZP1","id":"G3NZP1_GASAC","source_organism":{"taxId":"481459","scientificName":"Gasterosteus aculeatus aculeatus","fullName":"Gasterosteus aculeatus aculeatus (three-spined stickleback)"},"name":"Secreted frizzled-related protein 3","description":["Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development"],"length":313,"sequence":"MLSPGLCVSLLAASCALWPAAAVRAASCESVRIPLCASMPWNMTKMPNHLHHSTQDNAVLAIEQYEGLLGTGCSPDLLFFLCAMYAPICTIDFQHEPIKPCKAVCERAKQGCEPVMKRYNHSWPDSLACSELPLYDRGVCISPEAIVKAEAPDPYPQDPARCNPESSPDFPMDSNNLHCRGPNADRCKCKTVKMGFKNYQRNNYNYVIRARVREVRNRGLEPTAVVEVKEVLKSSLVNIPKETQTLYYSSSCLCPPLSPGEEYLIMGYENDEMSRLLLIDGSIAQKWREKMSRKIKLHSVTLSVAPFLHLATA","proteome":"UP000007635","gene":null,"go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"f8a655922328c0c2a242c85dc64e70c2a18e5657","counters":{"domain_architectures":3784,"entries":17,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"profile":2,"cathgene3d":2,"ssf":2,"smart":2,"pfam":2,"panther":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":3784}}}