{"metadata":{"accession":"G2Q9T3","id":"LP9H_THET4","source_organism":{"taxId":"573729","scientificName":"Thermothelomyces thermophilus (strain ATCC 42464 / BCRC 31852 / DSM 1799)","fullName":"Thermothelomyces thermophilus (strain ATCC 42464 / BCRC 31852 / DSM 1799)"},"name":"AA9 family lytic polysaccharide monooxygenase H","description":["Lytic polysaccharide monooxygenase (LPMO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 or C4 oxidation products (PubMed:22342036, PubMed:35450635). Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate (Probable). Hydrolyzes weakly barley beta-glucan, carboxymethyl cellulose, lichenan, wheat arabinoxylan and birchwood xylan (PubMed:22342036, PubMed:35450635). Stimulates the hydrolysis of lignocellulosic substrates (such as hydrothermal pretreated wheat straw or steam-pretreated spruce), when combined with other cellulolytic enzymes (PubMed:22342036)"],"length":342,"sequence":"MSKASALLAGLTGAALVAAHGHVSHIVVNGVYYRNYDPTTDWYQPNPPTVIGWTAADQDNGFVEPNSFGTPDIICHKSATPGGGHATVAAGDKINIVWTPEWPESHIGPVIDYLAACNGDCETVDKSSLRWFKIDGAGYDKAAGRWAADALRANGNSWLVQIPSDLKAGNYVLRHEIIALHGAQSPNGAQAYPQCINLRVTGGGSNLPSGVAGTSLYKATDPGILFNPYVSSPDYTVPGPALIAGAASSIAQSTSVATATGTATVPGGGGANPTATTTAATSAAPSTTLRTTTTSAAQTTAPPSGDVQTKYGQCGGNGWTGPTVCAPGSSCSVLNEWYSQCL","proteome":"UP000007322","gene":"LPMO9H","go_terms":[{"identifier":"GO:0030248","name":"cellulose binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005975","name":"carbohydrate metabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005576","name":"extracellular region","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"0ee351bc19c4eac8c2647414ef821eabcc14df1e","counters":{"domain_architectures":2831,"entries":13,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cdd":1,"cathgene3d":1,"profile":1,"ssf":1,"smart":1,"pfam":2,"panther":1,"prosite":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":2831}}}