{"metadata":{"accession":"G1NYB0","id":"G1NYB0_MYOLU","source_organism":{"taxId":"59463","scientificName":"Myotis lucifugus","fullName":"Myotis lucifugus (Little brown bat)"},"name":"Polypeptide N-acetylgalactosaminyltransferase","description":["Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward non-glycosylated peptides such as Muc5AC, Muc1a and EA2, and no detectable activity with Muc2 and Muc7. Displays enzymatic activity toward the Gal-NAc-Muc5AC glycopeptide, but no detectable activity to mono-GalNAc-glycosylated Muc1a, Muc2, Muc7 and EA2. May play an important role in the initial step of mucin-type oligosaccharide biosynthesis in digestive organs"],"length":579,"sequence":"GRSLRRTRGLRRGHGKIEGMMELHILVQSGLGLGCLSGQRQRGAKTAEPRPCGTPRSGRRDPVLPRPPCRRTPWAARGEAVRLQLEGEELRLQEEVRLHQINTYLSDRISLHRRLPERWNPLCKEKKYDYDQLPTTSIIIAFYNEAWSTLLRTVYSVLETSPDILLEEVILVDDYSDREHLKERLENELSKLPKVRLIRANKREGLVRARLLGASVAKGQVLTFLDCHCECHEGWLEPLLQRIQEEESAVVCPVIDVIDWNTFEYLGNSGEPQIGGFDWRLVFTWHVVPERERMRMRSPVDVIRSPTMAGGLFAVSKKYFEYLGSYDTGMEVWGGENLEFSFRIWQCGGTLETHPCSHVGHVFPKQAPYSRKKALANSVRAAEVWMDEFKELYYHRSPHARLEPFGDVTERKQLRAKLQCKDFKWFLETVYPELHVPEDRPGFFGMLQNKGLKDYCFDYNPPSEHDLTGHQVLLYLCHGMGQNQFFEHTSQNEIRYNTHQPEACIAVEAGTDILIMHLCQDTAPENQKFILQEDGSLFHIQSKKCVQAEKKALSNSFVPLLRDCTNSEHQKWFFKERMS","proteome":"UP000001074","gene":"GALNT12","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"4220cc2d6b80a4cae68dbc82f30d6bc6446fd974","counters":{"domain_architectures":21176,"entries":15,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"ssf":2,"pfam":2,"cdd":1,"profile":1,"smart":1,"panther":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":21176}}}