{"metadata":{"accession":"G1NNY7","id":"G1NNY7_MELGA","source_organism":{"taxId":"9103","scientificName":"Meleagris gallopavo","fullName":"Meleagris gallopavo (Wild turkey)"},"name":"Vacuolar protein sorting-associated protein 26C","description":["Component of the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex. Component of the retriever complex, which is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retriever and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling"],"length":297,"sequence":"MGTALDIKIKRANKVYHCGEILSGVVVITSKDTVQHQGISLTMEGSVNLQLSAKSVGVFEAFYNSVKPIQIINSTIEMVKPGKLPSGKTEIPFEFPLHVKGNKVLYETYHGVFVNIQYTLRCDMRRSLLAKDLTKTCEFIVHSVSQKGKLTPSPVDFTITPETLQNVKERASLPKFLIRGHLSSTNCIITQPLTGELVVESAEAAVKSIELQLVRVETCGCAEGYARDATEIQNIQIADGDVCRGLPIPIYMVFPRLFTCPTLETTNFKVEFEVNIVVLLHDDHLITENFPLKLCRM","proteome":"UP000001645","gene":"VPS26C","go_terms":[{"identifier":"GO:0006886","name":"intracellular protein transport","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"48a17636f5b7a8739160239fa50118fb5e352930","counters":{"domain_architectures":9584,"entries":7,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"panther":1,"pfam":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":9584}}}