GET /api/protein/UniProt/G1MSS6/?format=api&page_size=20
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Content-Type: application/json
InterPro-Version: 109.0
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{
"metadata": {
"accession": "G1MSS6",
"id": "G1MSS6_MELGA",
"source_organism": {
"taxId": "9103",
"scientificName": "Meleagris gallopavo",
"fullName": "Meleagris gallopavo (Wild turkey)"
},
"name": "Anti-Muellerian hormone",
"description": [
"The anti-Muellerian hormone (AMH) plays an important role in several reproductive functions. Anti-Muellerian hormone binds and activates AMHR2, its specific type-II receptor, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A) to regulate target gene expression through downstream SMAD protein signal transduction. Produced and secreted by Sertoli cells of the male fetus, anti-Muellerian hormone induces Muellerian duct regression during male fetal sexual differentiation. In female, it is produced by granulosa cells of the preantral and small antral follicles and acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles. Also plays a role in Leydig cell differentiation and function"
],
"length": 529,
"sequence": "MRRAPPSCRSLPQRGTIGDAGFEPVAPRRAPPTLAGRSQSEPSGCSARTGGAHPMLWGCSAHTGGAQLPHALLPSLPVLPSLTSSRASSLHTLGWISPWVLGKQGLDCRGVLLTPVMPPAGSQGLLCLCSPQSLCFTRDTQYLLLRASVAAVTSSSKELSFQHWGPGAPLSLMETQQLLFGSDEKCFTRMTPVLLLLAGSTPEDDAASPSSYLSASGVVDVAPYPQLSPPHPGTAEPPSHTTASPANTTSPTAGDSGQFLGVLTLFIRRVLSPRSEPPTQPSSQHWLDFQMMETLPHQLLNLSETAALERLVQSEEPSVLLFPQEGGVGLEQHFGDWQLEGTVLQLLMGKLQAVIHDLRDIPEFQANTGLFQQLLSFCYHPPGPAAGGQPPGSGKLHALLLLKALQTVRARWQERRKVLRQNRSARHQAHCRLQELTIDLRDRNFIVMPTVYAANNCEGPCKLPLSTRVPGYHSHTVLLLGMQERGSPLQRAPCCVPVRYSDQLIISVSAEGLEVRKFPNMVAEECGCR",
"proteome": "UP000001645",
"gene": null,
"go_terms": [
{
"identifier": "GO:0008083",
"name": "growth factor activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0008406",
"name": "gonad development",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"ida_accession": "22f13bac5db31f04633d2f53e0b703352eccbff6",
"counters": {
"domain_architectures": 821,
"entries": 14,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"profile": 1,
"cathgene3d": 1,
"ssf": 1,
"pfam": 2,
"cdd": 1,
"smart": 1,
"panther": 1,
"prosite": 1,
"interpro": 5
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 821
}
}
}